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Participants
Agenda
Background Materials
  • IMMPACT-X Slide Presentations

  • 1. Scope of the problem of prescription opioid abuse: public health perspective
  • Richard A. Denisco, MD
  • 2. Deterrence of prescription opioid abuse: FDA perspective
  • Bob A. Rappaport, MD
  • 3. Clinical studies of abuse deterrent opioid analgesics: definitions, current approaches, and critical issues
  • Nathaniel P. Katz, MD
  • 4. Current status of experimental human abuse liability studies: methods, outcomes, and predictive validity for real-world abuse
  • Sandra D. Comer, PhD
  • 5. Limitations of experimental human abuse liability studies and prospects for improvement
  • James P, Zacny, PhD
  • 6. Retrospective analyses of abuse-related outcomes in clinical trials of analgesic drugs and their interpretation
  • Michael Klein, PhD
  • 7. How can abuse-related outcomes be prospectively evaluated in clinical trials of analgesic drugs?
  • Deborah B. Leiderman, MD
  • 8. Randomized clinical trials of abuse: limitations and prospects for improvement
  • Edgar H. Adams, ScD
  • 9. Observational and claims data studies of abuse-related outcomes: limitations and prospects for improvement
  • Nabarun Dasgupta, MPH
  • 10. The use of poison center data to assess the relative abuse rates of prescription opioids
  • Richard Dart, MD, PhD
  • 11. The use of addiction center data to assess abuse of prescription opioids
  • John Brownstein, PhD