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Participants
Agenda
Background Materials
  • IMMPACT-IX Slide Presentations

  • 1. Proof-of-concept trials: industry perspective
  • Christine Rauschkolb, MD, PhD
  • 2. Proof-of-concept trials: academic perspective
  • Ian Gilron, MD
  • 3. Single-dose and short-term proof-of-concept trials in neuropathic pain
  • Srinivasa Raja, MD
  • 4. Single-dose and short-term proof-of-concept trials in non-neuropathic pain
  • Nat Katz, MD
  • 5. Statistical considerations in small proof-of-concept trials, including crossover designs
  • Stephen Senn, PhD
  • 6. Futility trials and other adaptive designs
  • Cyrus Mehta, PhD
  • 7. Dosage determination from preclinical to proof-of-concept trials
  • Charles Taylor, PhD
  • 8. PK-PD modeling and dosage determination for proof-of-concept trials
  • Marc Gastonguay, PhD
  • 9. Phenotyping chronic pain patients for proof-of-concept trials
  • Ralf Baron, MD